The 2018 NFL regular season concludes with plenty of drama around the league as there are two playoff spots available in the AFC – including two division titles – and one postseason opening in the NFC but no division crowns up for grabs.

Odds courtesy of OddsShark.com

There is one winner-take-all game and it was flexed to the prime-time window as the Indianapolis Colts visit the Tennessee Titans, who are 3.5-point underdogs. The winner is in the playoffs as at worst a wild-card team and would win the AFC South Division if the Houston Texans lose as 7-point home favorites against the Jacksonville Jaguars.

Will the Titans have starting quarterback Marcus Mariota? That’s the big question after he left Week 16 with an elbow injury, a problem that has plagued him all year. Last thing the Titans need considering they are 2-12 SU and 3-11 against the spread in the past 14 against the Colts. The Titans-Colts winner probably won’t be taking the division if recent history is any indication as the Jaguars are 2-13 SU in their past 15 road games inside the AFC South.